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Washington DC Area Mathematica Special Interest Group

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  • Subject: [mg107477] Washington DC Area Mathematica Special Interest Group
  • From: "Bruce Colletti" <bwcolletti at>
  • Date: Sun, 14 Feb 2010 05:57:47 -0500 (EST)

Mathematica SIG


19 February  2010, 7:30 am

Science Applications International Corporation (SAIC)
8301 Greensboro Drive
McLean VA

Southern Corner of Westpark Drive and Greensboro Drive


1.  Prepared Talks

Developing Interactive Visualization Tools in Mathematica to Analyze
Regulatory Issues for Biologics Products, by Richard Forshee (speaker), Mark
Walderhaug, Anne Fernando, Arianna Simonetti, Elliot Cowan, Hilary Hoffman

ABSTRACT.  Interactive visualization tools are useful for analyzing and
communicating complex regulatory problems.  The Center for Biologics
Evaluation and Research has recently presented new visualization tools to
study the comparative benefits and risks of hypothetical alternative medical
products and to analyze the public health implications of a hypothetical
home-use HIV test kit. 

One of the challenges for Benefit:Risk analysis is to develop tools to help
decision-makers analyze the benefits and risks of products while properly
characterizing the uncertainty of the estimates of benefits and risks. We
have developed a three-dimensional visualization tool where the height of
the surface represents the probability that the treatment has a particular
risk-benefit coordinate.  The visualization tool allows users to compare two
therapeutics. The tool shows key properties of distributions that may affect
decision-making; integrates data on multiple properties of a medical
product; and encourages stakeholders to interact with the visualization to
explore what-if scenarios.

Home-use HIV test kits can potentially identify many HIV-positive
individuals who are unaware of their status, but they may also produce a
large number of incorrect test results because of user error.  We have
developed an analytic tool to estimate the public health benefits and risks
of a home-use HIV test kit.

These two projects demonstrate the utility of using interactive
visualization tools to analyze and communicate complex regulatory issues.

User-Controlled Data Acquisition Using Mathematica, by Dan Martinez

ABSTRACT.  Dan will discuss two applications:  acquiring data used in
process analysis or queuing theory, and the other in tallying one's book
reading rate, e.g., seconds/page.

Constructing Equivalence Relations, by Bruce Colletti

ABSTRACT.  In this brief talk, Bruce will demonstrate how to use
Combinatorica (a built-in package of Mathematica) to build and display
equivalence relations.

2.  Mathematica Gems and Discoveries

- Sharing of Mathematica programming oddities
- Applications of Mathematica to some areas of science
- Something recently read and worth sharing

3.  Mathematica Questions, Possible Approaches and Discussion

4.  New Business

- Select next meeting presentation, time and place

Directions to 8301 Greensboro Drive, McLean VA (tall, boxy and white SAIC
Enterprise Building at south corner of Westpark Drive and Greensboro Drive):

>From the Beltway, go northwest on Route 7 (Leesburg Pike) and proceed past
Route 123 (Chain Bridge Road). Turn right onto Westpark Drive (Gosnell Road
in the other direction). Turn right at the next light onto Greensboro Drive
and then right into the parking lot. Visitor's Parking is adjacent to
Westpark Drive.

A SIG representative will meet you in the lobby.

Please arrive no later than 6:50AM if you wish to join us for a dutch-treat
breakfast, and no later than 7:20AM to attend the meeting only. The desk
officer will ask for a driver's license before issuing a visitor's badge.

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