Washington DC Area Mathematica Special Interest Group
- To: mathgroup at smc.vnet.net
- Subject: [mg107477] Washington DC Area Mathematica Special Interest Group
- From: "Bruce Colletti" <bwcolletti at verizon.net>
- Date: Sun, 14 Feb 2010 05:57:47 -0500 (EST)
Mathematica SIG (http://web.mac.com/hrbishop.pmsi/DCSIG.m/DCSIG.html) MEETING 19 February 2010, 7:30 am Science Applications International Corporation (SAIC) 8301 Greensboro Drive McLean VA Southern Corner of Westpark Drive and Greensboro Drive Agenda 1. Prepared Talks Developing Interactive Visualization Tools in Mathematica to Analyze Regulatory Issues for Biologics Products, by Richard Forshee (speaker), Mark Walderhaug, Anne Fernando, Arianna Simonetti, Elliot Cowan, Hilary Hoffman ABSTRACT. Interactive visualization tools are useful for analyzing and communicating complex regulatory problems. The Center for Biologics Evaluation and Research has recently presented new visualization tools to study the comparative benefits and risks of hypothetical alternative medical products and to analyze the public health implications of a hypothetical home-use HIV test kit. One of the challenges for Benefit:Risk analysis is to develop tools to help decision-makers analyze the benefits and risks of products while properly characterizing the uncertainty of the estimates of benefits and risks. We have developed a three-dimensional visualization tool where the height of the surface represents the probability that the treatment has a particular risk-benefit coordinate. The visualization tool allows users to compare two therapeutics. The tool shows key properties of distributions that may affect decision-making; integrates data on multiple properties of a medical product; and encourages stakeholders to interact with the visualization to explore what-if scenarios. Home-use HIV test kits can potentially identify many HIV-positive individuals who are unaware of their status, but they may also produce a large number of incorrect test results because of user error. We have developed an analytic tool to estimate the public health benefits and risks of a home-use HIV test kit. These two projects demonstrate the utility of using interactive visualization tools to analyze and communicate complex regulatory issues. User-Controlled Data Acquisition Using Mathematica, by Dan Martinez ABSTRACT. Dan will discuss two applications: acquiring data used in process analysis or queuing theory, and the other in tallying one's book reading rate, e.g., seconds/page. Constructing Equivalence Relations, by Bruce Colletti ABSTRACT. In this brief talk, Bruce will demonstrate how to use Combinatorica (a built-in package of Mathematica) to build and display equivalence relations. 2. Mathematica Gems and Discoveries - Sharing of Mathematica programming oddities - Applications of Mathematica to some areas of science - Something recently read and worth sharing 3. Mathematica Questions, Possible Approaches and Discussion 4. New Business - Select next meeting presentation, time and place Directions to 8301 Greensboro Drive, McLean VA (tall, boxy and white SAIC Enterprise Building at south corner of Westpark Drive and Greensboro Drive): >From the Beltway, go northwest on Route 7 (Leesburg Pike) and proceed past Route 123 (Chain Bridge Road). Turn right onto Westpark Drive (Gosnell Road in the other direction). Turn right at the next light onto Greensboro Drive and then right into the parking lot. Visitor's Parking is adjacent to Westpark Drive. A SIG representative will meet you in the lobby. Please arrive no later than 6:50AM if you wish to join us for a dutch-treat breakfast, and no later than 7:20AM to attend the meeting only. The desk officer will ask for a driver's license before issuing a visitor's badge.