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MathGroup Archive 2004

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Biokmod 3.2 for solving compartmental, biokinetic and ICRP models

  • To: mathgroup at smc.vnet.net
  • Subject: [mg51435] Biokmod 3.2 for solving compartmental, biokinetic and ICRP models
  • From: guillerm at aida.usal.es (Guillermo Sanchez)
  • Date: Sun, 17 Oct 2004 03:05:32 -0400 (EDT)
  • Sender: owner-wri-mathgroup at wolfram.com

I release Biokmod 3.2 (standard). It can be downloaded from
http://web.usal.es/~guillerm/biokmod.htm

Also, there are a webMathematica application of  Biokmod called
BiokmodWeb (available in
http://www3.enusa.es/webMathematica/Public/biokmod.html ). It runs on
line, you don't need to download any thing in your computer. It
contains most of the main features of the Mathematica Tool Biokmod


Biokmod include 

I.-  Functions for solving compartmental models (with application in
biokinetic, pharmacokinetic,  internal dosimetry and nuclear medicine)

I.1) The user can himself define compartmental models obtaining the
differential equations, their solutions, graphic representation and Us
(disintegrations).
I.2) Options for fitting coefficients in linear differential equations
are included.

II.-  Features to evaluate the intake of radioactive particles in the
human body according ICRP Models

II.1) The respiratory tract model (according ICRP 66) for modelling
the intake of radioactive aerosols is solved. Gives the Intake
Retention Fractions (IRF), their analytical expressions, the Intake
Retention Functions (RF), and the graphic representation.
II.2) Radioactive intake by injection, ingestion and inhalation in the
human body according ICRP models
II.3) Acute, Chronic, Continuous (variable in the time) , Multi-Acute
and randon intakes can be simulated.
II.4) Analytical and numeric solutions are given. 
II.5) Disintegrations (Us) over at time t -choose by user- are
computed analytically (better than using mean residence time).

III.- Some tutorials and a complete help is included


I will appreciate any comments.

Guillermo Sanchez

http://web.usal.es/~guillerm/


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