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MathGroup Archive 2007

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Updated BiokmodWeb, the web version of BIOKMOD

  • To: mathgroup at smc.vnet.net
  • Subject: [mg75191] Updated BiokmodWeb, the web version of BIOKMOD
  • From: Guillermo Sanchez <guillermo.sanchez at hotmail.com>
  • Date: Fri, 20 Apr 2007 00:34:24 -0400 (EDT)

BiokmodWeb has been updated. It is the web version of BIOKMOD a
program to be applied in pharmacokinetic, internal dosimetry, bioassay
data evaluation and nuclear medicine. It has been developed using
Mathematica, webMathematica and Java. It runs on line, you do not need
other think that your browser. It is available at the webside

http://www3.enusa.es/webMathematica/Public/biokmod.html,

It contains some features of BIOKMOD below summarized
Building compartmental models (constant and variable coefficients can
be used) in a very easy way generating automatically the system of
differential equations and their solutions, graphic representation and
US (disintegrations). A specific function for multiinputs (single and
constant inputs) is included.
 Solving ICRP Models for practically all isotopes (including some
specific options for Lung and Respiratory Tract) obtaining the Intake
Retention Fractions (IRF), their analytical expressions (intake
retention functions), the compartmental contents and the graphic
representations. Acute, constant -chronic, continuous (variable in the
time) and multi-inputs,  even random, intakes can be used. You can
accepted the default parameters or introduce specific values.
Fitting functions for bioassay data evaluation (many parameters of the
ICRP models can be fitted).
To compute the committed doses for some isotopes using non standard
values. It can be expanded for many isotopes computing the accumulated
disintegrations (with the function Desintegrations) and using the SEE
factor supplied by other free programs as DCAL .
An optimal design function is included. It can be used to establish
the best moment where experimental sample or bioassay should be taken.
A function for evaluating uncertainties analytically is available.
Additional utilities

The BiokmodWeb is considerably expanded by BIOKMOD 4 (Mathematica is
required). Some papers have been published describing some of the
methods used by BIOKMOD
 For additional information visit the author website: http://web.usal.es/gu=
illermo.

Guillermo S=E1nchez



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