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help: how to fit a list of data in two dimensions with an equation in

Hello everyone and thanks for your help.
I have the following problem, I have ten lists of
p1={{41., 4.27541}, {41., 4.27576}, {41., 4.27518}, {41.,

the lists of numbers are data where the first term is time and second
a concentration: {time,concentration}
now I have a function where the concentration is a function of the
time and 2 other parameters: c=f(kr, kc, time).

How to fit the lists of data  {time,c} with c=f(time, kc,kr) by
finding the couple {kr,kc} for each list?
In other words I'd like to find 10 couples of {kr,kc} fitting the
equation c=f(time, kc,kr)

Thanks again all of you.

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